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1

BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity

Rudolph, D., Steegmaier, M., Hoffmann, M., Grauert, M., Baum, A., Quant, J., Haslinger, C., Garin-Chesa, P., Adolf, G. R.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 479 KB

english, 2009

2

P-selectin glycoprotein ligand-1 mediates rolling of mouse bone marrow-derived mast cells on P-selectin but not efficiently on E-selectin

Martin Steegmaier, James E. Blanks, Eric Borges, Dietmar Vestweber

Journal:

European Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 744 KB

english, 1997

3

SNARE Protein Trafficking in Polarized MDCK Cells

Martin Steegmaier, Kelly C. Lee, Rytis Prekeris, Richard H. Scheller

Journal:

Year:

2000

Language:

english

File:

PDF, 427 KB

english, 2000

4

The Small-Molecule Inhibitor BI 2536 Reveals Novel Insights into Mitotic Roles of Polo-like Kinase 1

Péter Lénárt, Mark Petronczki, Martin Steegmaier, Barbara Di Fiore, Jesse J. Lipp, Matthias Hoffmann, Wolfgang J. Rettig, Norbert Kraut, Jan-Michael Peters

Journal:

Current Biology

Year:

2007

Language:

english

File:

PDF, 2.43 MB

english, 2007

5

BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo

Martin Steegmaier, Matthias Hoffmann, Anke Baum, Péter Lénárt, Mark Petronczki, Martin Krššák, Ulrich Gürtler, Pilar Garin-Chesa, Simone Lieb, Jens Quant, Matthias Grauert, Günther R. Adolf, Norbert K

Journal:

Current Biology

Year:

2007

Language:

english

File:

PDF, 1003 KB

english, 2007

6

356 POSTER In vivo efficacy of BI 2536, a potent and selective inhibitor of the mitotic kinase PIK1, in combination with various cytotoxic agents

A. Baum, U. Gürtler, G. Munzert, M. Steegmaier

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 73 KB

english, 2006

7

468 POSTER In vivo imaging of apoptosis induction by BI 2536, a small-molecule inhibitor of human Polo-like kinase 1 (PIK1), in human cancer xenograft models

M. Krssák, U. Gürtler, S. Fischer, R. Klaus, M. Steegmaier

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 70 KB

english, 2006

8

430 POSTER Characterization of BI 6727, a novel Polo-like kinase inhibitor with a distinct pharmacokinetic profile and efficacy in a model of taxane-resistant colon cancer

D. Rudolph, M. Steegmaier, M. Hoffmann, M. Grauert, A. Baum, J. Quant, P. Garin-Chesa, G. Adolf

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 63 KB

english, 2008

9

L-Selectin from Human, but Not from Mouse Neutrophils Binds Directly to E-Selectin

Olaf Zöllner, Martin C. Lenter, James E. Blanks, Eric Borges, Martin Steegmaier, Hans-Günther Zerwes and Dietmar Vestweber

Journal:

The Journal of Cell Biology

Year:

1997

Language:

english

File:

PDF, 2.48 MB

english, 1997

10

nSec1 Binds a Closed Conformation of Syntaxin1A

Bin Yang, Martin Steegmaier, Lino C. Gonzalez, Jr. and Richard H. Scheller

Journal:

The Journal of Cell Biology

Year:

2000

Language:

english

File:

PDF, 1.51 MB

english, 2000

11

Syntaxin 17 Is Abundant in Steroidogenic Cells and Implicated in Smooth Endoplasmic Reticulum Membrane Dynamics

Steegmaier, M., Oorschot, V., Klumperman, J., Scheller, R. H.

Journal:

Molecular Biology of the Cell

Year:

2000

Language:

english

File:

PDF, 1.41 MB

english, 2000

12

The Binding of T Cell-expressed P-selectin Glycoprotein Ligand-1 to E- and P-selectin Is Differentially Regulated

Borges, E., Pendl, G., Eytner, R., Steegmaier, M., Zollner, O., Vestweber, D.

Journal:

Journal of Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 749 KB

english, 1997

13

Vesicle-associated Membrane Protein 4 is Implicated in Trans-Golgi Network Vesicle Trafficking

Steegmaier, M., Klumperman, J., Foletti, D. L., Yoo, J.-S., Scheller, R. H.

Journal:

Molecular Biology of the Cell

Year:

1999

Language:

english

File:

PDF, 2.30 MB

english, 1999

14

SNARE Interactions Are Not Selective: IMPLICATIONS FOR MEMBRANE FUSION SPECIFICITY

Yang, B., Gonzalez, L., Prekeris, R., Steegmaier, M., Advani, R. J., Scheller, R. H.

Journal:

Journal of Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 714 KB

english, 1999

15

Three Novel Proteins of the Syntaxin/SNAP-25 Family

Journal:

Journal of Biological Chemistry

Year:

1998

Language:

english

File:

PDF, 957 KB

english, 1998

16

Localization, Dynamics, and Protein Interactions Reveal Distinct Roles for ER and Golgi SNAREs

Jesse C. Hay, Judith Klumperman, Viola Oorschot, Martin Steegmaier, Christin S. Kuo and Richard H. Scheller

Journal:

The Journal of Cell Biology

Year:

1998

Language:

english

File:

PDF, 5.70 MB

english, 1998

17

BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

Sapkota, Gopal P., Cummings, Lorna, Newell, Felicity S., Armstrong, Christopher, Bain, Jennifer, Frodin, Morten, Grauert, Matthias, Hoffmann, Matthias, Schnapp, Gisela, Steegmaier, Martin, Cohen, Phil

Journal:

Biochemical Journal

Year:

2007

Language:

english

File:

PDF, 661 KB

english, 2007

18

The P-Selectin Glycoprotein Ligand-1 Is Important for Recruitment of Neutrophils Into Inflamed Mouse Peritoneum

Borges, Eric, Eytner, Ruth, Moll, Thomas, Steegmaier, Martin, Campbell, Matthew A., Ley, Klaus, Mossmann, Horst, Vestweber, Dietmar

Journal:

Year:

1997

File:

PDF, 273 KB

1997

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